His Brain, Her Brain, or Why it Took Moses 40 Years to Find His Way Out of the Desert.
One fascinating point Dryer shared was that although we all know that someone with the XX chromosome set is female, and the males are XY, it's not 'either-or'. During gestation, at about the 6-8 week point, the fetus undergoes a 'hormone wash', which may be highly loaded with estrogen or testosterone. This overlays brain development and influences brain function. So, there's really a continuum of sexuality.
And – all of these points are generalizations. There will always be exceptions. Don't shoot the messenger. I'm sharing my notes here.
There are definite differences in brain structure in males and females. Differences are noted at 26 weeks of pregnancy. The brain develops differently in males before sex hormones are produced, so part of the sex differences in the brain is genetic.

Now, cutting to the chase: Humans started out a long, long time ago. Changes in the brain are nowhere near catching up. So, we're basically hard-wired to survive, but not in this century. Traveling back to the days of early man…
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Males are hard-wired as hunters. They have better long range directional skills. They've got a better spatial sense. They focus on single tasks, on procreation, they focus on things.
Females are hard-wired as protectors of the nest. They're communal, have more finely tuned sensory skills, are multi-taskers. They're non-verbal communicators. They can process and integrate input faster.
Some differences (and remember, these are generalizations)
The male resting brain is 30% active.
The female resting brain is 90% active. (So, yeah, it's hard for us to 'shut down')
The male brain is logical.
The female brain is emotive.
The male brain is left hemisphere dominant, with the exception of the spatial area.
The female brain is more multi-hemisphere, with a thicker Corpus Callosum.
When men speak, only one site is active. (Right—they talk OR listen.)
When women speak, both the hearing and speech centers are active.
On the topic of lying:
Women lie to make others feel better
Men lie to make themselves look good.
Men don't lie more than women, they just get caught.
Women lie for self-deception
If a man and a woman are in a close relationship, it's harder to lie.
